If you start from Villes-sur-Auzon you can ride through the Gorges de la Nesque, which are magnificent, then through the lavender fields up to Sault. From there it's an easy ride to Chalet-Reynard, and then somewhat less easy to reach the top.
If you start from Bédoin you can compare yourself with the TdF riders. A chacun son gout. Personally, I found the slog up through the forest a bind: it can get extremely hot, the flies are numerous, and you can't see anything but trees until you reach Chalet Reynard.
Last time I did it I started from Orange in the cool early morning, then rode to Le Barroux and over the little col that separates it from Malaucène. This is around 33k, a nice warm-up. Riders were dribbling into the café opposite the start of the climb: I had a coffee and a pain chocolat and then started up. It was a clear day, and practically all the way I had magnificent the views of the distant Alps off to the side. All the way up I was passing and being passed by riders from all over the world, and everyone was jolly. I'd say the slopes are stiffer than on the Bédoin side, but as compensation you get a few easy stretches to recover on. There's one point, though, where you round a bend and see the relay tower at the top hanging over you: it looks almost straight up. Something of an "oh my God" moment.
What's great, though, is cycling down the Bédoin side. The curves are easy, the tarmac is smooth, and you can put your nose down and motor. Not my fastest descent but definitely the one I want to repeat.
So for me, absolutely the best way to do it is to climb from Malaucène then zoom down to Bédoin. Then toddle on to Carpentras and have a good lunch to celebrate.
Or: you can pick up the route card for the Cinglés du Mont Ventoux and do it from all three classic starting points in the one day. You can then join one of two distinguished fraternities: the Cinglés du Mont Ventoux, or Intensive Care Past Pupils.
Heh: first time I did it was with a bunch, and at the top we paused for the customary photo:

A couple of weeks later I showed it to a friend, modestly refraining from comment. Friend: "Oh, you were at the seaside!"
Back in 2004 we went via Sault to C-R on the same day as the Dauphiné Libéré Time Trial. That's worth a go:
http://www.pbase.com/johnewing/image/122488471
