Hi Ken, and welcome to the forum!
I've not studied the Cirerone Route to be honest. From what I make out from what I've seen, they send you over Dartmoor.
Sorry, I would never agree to send someone over Dartmoor on an End2End as it's too tough. If you want to "do" Dartmoor, come down and stay over for a weekend, and you can do the whole lot as a separate thing rather than tiring you out on only your second day from LE.
It's a long way. In the region of 900miles. Even doing 80miles a day, it'll take you the best part of a fortnight, so in my opinion, you should make it as easy as you can. If there are places you want to visit and ride through, do it as a separate thing .......... like Dartmoor.
I spent some time writing out in detail the instructions but it's a bit wordy. It would be better if I got off my bum and found an online mapping program that I like so I can draw it out and give a link. I had one done, but BikeHikeUK stopped hosting links, so I then went to BikeRouteToaster and transferred them over, but I think even that's defunct now.

So I'll need to start again with a new map.
Rather than post the whole thing on one post, I'll do it in chapters.
Chapter One now, and subsequent chapters tomorrow and onwards.
You’ll need a good road atlas to follow my instructions.
Basic route is:
LE, Okehampton, Crediton, Tiverton, Taunton, Bridgwater, Bristol
Severn Bridge, Monmouth, Hereford, Leominster
- OR -
Gloucester, Ledbury, Leominster
Ludlow, Shrewsbury, Whitchurch, Warrington, Wigan, Euxton, Preston
Garstang. Lancaster, Kendal, Penrith, Carlisle
Lockerbie, Moffat, Edinburgh
- OR -
Langholm, Hawick, Galashiels, Edinburgh
Perth, Pitlochry, Inverness, Dingwall, Golspie, Brora, Helmsdale, Wick, JOG.
Chapter One
From LE follow the A30 to Penzance.
You can either go through the town centre or follow the bypass round to the north of the town. Either way, you end up on a roundabout on the A30 and follow this to another big roundabout where you can bear left for Hayle.
Go through the centre of Hayle and come out at another A30 roundabout. Take the second exit signposted Connor Downs. This is the Old A30 and you’ll be getting on and off that until you reach Okehampton.
Go over the Downs, and keep going and through Camborne town centre and into Redruth town centre following the old roads and the route of the Old A30. After Redruth, head for Scorrier and Blackwater again on the Old A30.
At the other end of Blackwater, you come to a roundabout at Three Burrows. Get on the A30. It’s single carriageway mainly and ok to cycle on. In the future, they are going to dual this stretch and I’m going to have to sort out a better cycling route!
You could turn off at Three Burrows onto the A3075 towards Newquay, but I think that’s taking you out of your way. Some folk have gone that way, then worked their way east back along the A392 through Quintrell Downs to pick up my described route.
Follow the A30 to Zelah - turn off the main road and go through the village Old A30 - and out again for a short time back on the A30 turning off left through St Newlyn East.
Cross the A3058 at Gummow’s Shop and cross the A392 at White Cross and go through St Columb Major. At the other end, pop out onto the A39 and head north and this will take you to Wadebridge. You can go down through the town, or stay up on the main road, but either way you will end up north of the town on the A39 heading for Camelford.
A few miles north of Camelford, turn east onto the A395 at Davidstow. Follow this through Hallworthy and over Wilsey Down and find a left turn onto minor roads to go through Tresmeer and Egloskerry. This road will take you to St Stephens just north of Launceston.
As you come out by the church, turn right onto the A388 (staggered junction) then immediately left and drop down into Newport at a mini roundabout opposite a Spar shop. Turn left up the hill a short way, then right. (east)
This road will take you to the north of Launceston on a fairly level road (Launceston town is high up on a hill with a Norman castle to your right). Pop out at a T junction and go right, following this to pop out onto the Old A30 by Launceston rugby ground and turn left.
Cross Polson Bridge over the border into Devon, and keep going.
Go through Lifton Down, Lifton, Tinhay, Portgate, Lewdown, Combebow, past Bridestowe, and climb up to nearly 1,000ft at Sourton where you turn left onto the A386 at a T junction.
Go under the A30 dual carriageway and follow the road past the services and Little Chef etc. Do not go onto the A30 despite the signpost for Okehampton.
Follow the A386 for less than a mile and see a small crossroads. Turn right signposted Meldon. This little road goes down hill and bends to the left and becomes an almost disused part of the Old A30, pop out onto the Old A30 proper, bearing left, and head into Okehampton town.
You are now about 100miles from LE and where most folk stop for their first night.